There was some interesting chatter on Twitter on Wednesday January 19, 2011 regarding tactics. @newbiedm mentioned wanting something akin to the “Player’s Strategy Guide” that Wizards of the Coast released, but for DMs. Basically, something that told DMs, “Okay, your party has x, y, z characters, here’s how you challenge them!”
As I wrote to both him and @SarahDarkmagic, I don’t believe that something like that is appropriate. I think that the key to challenging PCs in a 4th Edition D&D encounter is building the enemy “party” just like a player party would. What you want to focus on is the tactics within the enemy party, rather than build ways to stop the players’ characters.